| Division | Date | Time | Home | Away | Referee |
| Premier B | 16/05/2022 | 6.30 | Patrician Cel | Cottage Cel | A Whelan |
| 16/05/2022 | 7.00 | Griffith Rvs | Real Transilvania | G Leeper | |
| 1 South | 16/05/2022 | 6.30 | Tallaght Town | Peamount Utd | G Geraghty |
| 2 South | 16/05/2022 | 8.00 | Larkview | Leicester Cel | P Larkin |
| Premier A | 20/05/2022 | 7.00 | Kilmore | Glenville | S Dyas |
| M Lynch | |||||
| W Gahan | |||||
| 20/05/2022 | 7.00 | Raheny | Sandyhill/Shangan | G Leeper | |
| B Hand | |||||
| S Hand | |||||
| 20/05/2022 | 7.00 | St Pauls | Templeogue | G Geraghty | |
| Premier B | 20/05/2022 | 7.00 | Cottage Cel | Real Transilvania | J Keating |
| 20/05/2022 | 7.15 | St Brendans/Dingle | Patricians | W Byrne | |
| 20/05/2022 | 7.00 | St Mary’s | Mountview | P Larkin | |
| 1 South | 20/05/2022 | 7.00 | Tallaght Town | Rathnew | |
| 21/05/2022 | 3.00 | Peamount Utd | St John Bosco | G Geraghty | |
| 21/05/2022 | 2.00 | Terenure | Manortown | G Berkovich | |
| 2 South | 20/05/2022 | 8.00 | Ballyoulster | Garden Co | |
| 20/05/2022 | 7.00 | Lazio | Pegasus St James | B Cleary | |
| 20/05/2022 | 7.00 | Dundrum Ath | Lourdes Cel | D Lauchesse | |
| 3 South | 19/05/2022 | 7.00 | Booth Road Cel | Spartak Dynamo | B Coghlan |
| 20/05/2022 | 7.00 | Walkinstown Utd | Harding | C McCarthy | |
| 20/05/2022 | 8.00 | St Fergals | OLV | Wicklow | |
| 20/05/2022 | 7.00 | Ballyfermot Utd | Marks Cel | G Berkovich | |
| 1 North | 20/05/2022 | 7.00 | Marino | Elm Mount | P Hughes |
| 20/05/2022 | 7.00 | Ballymun Utd | Coolock Village | J Jackson | |
| 21/05/2022 | 2.00 | Swords Cel | Ashbourne | B Emerson | |
| 2 North | 20/05/2022 | 7.00 | Clontarf Ath | Celtic Park | C Hanlon |
| 20/05/2022 | 7.00 | Malahide Utd | Greenfield Pk | B Emerson | |
| 20/05/2022 | 7.00 | Lusk Utd | St Brendans Dingle | A Whelan | |
| 20/5/2022 | 7.0 | Dunshaughlin Yths | Stoneybatter Ath | S McCall | |
| 3 North | 20/05/2022 | 7.00 | Kinsealy Utd | Portrane Ath | R Lynch |
| 21/05/2022 | 3.00 | Ely Woodlawn | Whitehall Rgs | R Lynch | |
| 21/05/2022 | 2.00 | Raheny Utd | McKelvey Cel | G Leeper | |
| 21/05/2022 | 2.00 | Swords Manor | Rivervalley Rgs | B Cleary | |
| Sunday | 20/05/2022 | 8.00 | Balrothery | Lorcan Cel | T Flynn |
| 20/05/2022 | 7.00 | Confey | Irishtown St Pats | S Vasilenko | |
| 22/05/2022 | 11.00 | Newlands Castle Park | Beggsboro | JJ Walsh | |
| 22/05/2022 | 11.00 | Hyde Pk | Sallynoggin Pearse | A Whelan | |
| 20/05/2022 | 7.00 | Markievitcz Cel | St Columbans | A Conroy |